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IMPRESS trial data on continuing tyrosine kinase inhibitor therapy after resistance development in lung cancer reported

Gefitinib is a type of drug known as a tyrosine kinase inhibitor, and it targets cells with EGFR mutations. Most patients with EGFR mutation-positive non-small cell lung cancer respond to first-line EGFR tyrosine kinase inhibitors, but later acquire resistance. The primary objective of the trial was to show whether there was a difference in progression-free survival when gefitinib was continued in this situation. “This study was designed to ...

Significant presence of women in oncology, but still under-representation in leadership positions, Greek survey shows

Women are indeed increasingly choosing oncology specialties in Greece, however, most decision-making posts are still dominated by men across the profession, in private practice, academia and national health environments. This needs to change, she said. The survey of 80 female members of the Hellenic Societies of Medical, Radiation and Surgical Oncology showed that while women were widely represented in workplaces, team leaders were men in 82% of ...

Many patients lack information about the use of targeted therapies, oncologists say

The results come from an online survey of 895 doctors from 12 countries in Europe, South America and Asia. All were practicing oncology specialists, with more than three years’ experience, treating more than fifteen patients a month. While 82% of those surveyed believed that deciding on a course of treatment is a process that should be shared between doctors and the patient, fewer than 23% of physicians believed their patients were always fully ...

ESMO 2014 Highlights

Melanoma and colorectal cancer are the main field of progress
Johann de Bono
ESMO 2014
Scientific Chair...

A CLEOPATRA vizsgálat - végleges teljes túlélési eredmény pertuzumabbal: 56,5 hónap

A pertuzumab hozzáadása a trasztuzumab terápiához 56,5 hónapos teljes túlélést eredményez HER2-pozitív metasztatikus emlőkarcinómában. Ez az eddigi leghosszabb túlélés előrehaladott emlőrákban folytatott fázis III vizsgálatban. A CLEOPATRA vizsgálatban 808, korábban kezeletlen, HER2-pozitív, metasztatikus emlőrákban szenvedő betegen értékelték a pertuzumab, trasztuzumab és kemoterápia hatékonyságát és ...

Customising chemotherapy in lung cancer: new phase II data reported in two late-breaking studies

Thymidylate synthase is one of the proteins that is targeted by pemetrexed which is the most widely used chemotherapeutic regimen in the treatment of non-squamous NSCLC,” explains study author Professor Myung-Ju Ahn, from the Section of Hematology-Oncology at Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. “In this study, we tried to evaluate whether expression of thymidylate synthase is a predictive ...

Docetaxel or pemetrexed in addition to cisplatin achieve comparable outcomes in non-squamous lung cancer

At the ESMO 2014 Congress in Madrid, Dr Young-Chul Kim from Chonnam National University Medical School, South Korea, reported the results of an open-label phase III trial that included 149 patients with non-squamous non-small cell lung cancer (NSCLC) conducted at 14 centres in South Korea. “We wanted to conduct this study because pemetrexed plus platinum chemotherapy is the most commonly used regimen for treating patients with non-squamous...

French studies measure benefits of colorectal cancer screening

The study included all residents aged between 50 and 74 years of age who had a first adenoma identified between January 1997 and December 2008. The researchers showed that 38.7% of these people had high-risk adenomas --meaning they were larger than 1 centimetre in diameter, involved the finger-like projections called villi in the intestinal lining, or exhibited a high grade of dysplasia....

What are the new results in lung cancer treatment?

Floriana Morgillo, ESMO Expert on Lung Cancer...

Érdekfeszítő újdonságok a tüdőrák kezelésében az ASCO kongresszuson

Az Amerikai Klinikai Onkológiai Társaság (ASCO) 2014-es, Chicagóban rendezett kongresszusán jelen volt az OLO.hu stábja, amelynek Dr. Jyoti Patel, a chicagói Northwestern University munkatársa, az ASCO tüdőrák-specialistája nyilatkozott a tüdőrák kezelésének, a kongresszus folyamán elhangzott újdonságairól. A professzor asszony kiemelte, hogy a tüdőrák kezelése a klinikai onkológia állandó fejlődésben levő ...

Progress in treatment of head & neck tumors

Interview with  Gregory Masters, ASCO Expert on Head&Neck Tumors, Lung Cancer, Medical Oncologist, Helen F. Graham Cancer Center & Research Institute, Newark...

The best scientific achievements of ASCO 2014

Interview with  Jedd D. Wolchok, Chair of Congress Scientific Program Committee, Chief, Melanoma and Immunotherapeutics Service at Memorial Sloan Kettering Cancer Center, New York
...

Present and future in oncology

Interview with Peter Yu, ASCO President-Elect,
Director of Cancer Research at Palo Alto Medical Foundation, San Francisco...

New Therapies Harness Power of the Immune System Against Cancer

New research on innovative immunotherapies for advanced or high-risk melanoma and cervical cancer were presented today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). These treatments used alone or in combination fight cancer by activating and amplifying the body’s immune response to the disease.

The new studies find high activity with investigative drugs for advanced melanoma, and show for the ...

Major Advances in Breast, Prostate and Colorectal Cancer Treatment Featured at ASCO’s Annual Meeting

Findings from four phase III clinical trials in breast, prostate, and colorectal cancers were released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies were presented in ASCO’s Plenary session, which features the meeting’s most important clinical cancer research with the greatest potential to impact patient care.

These pivotal studies reveal new ways to optimize commonly used chemotherapy, ...

Studies Reveal Potential New Targeted Therapies for Common, Hard-to-Treat Cancers

Positive results from four clinical trials of investigational targeted drugs for advanced ovarian, lung, and thyroid cancers, and chronic lymphocytic leukemia were highlighted on Saturday at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). Findings from the mid- and late-stage trials suggest new ways to slow disease progression and improve survival for patients who experience relapses or resistance to available ...

New Strategies to Improve Quality of Life for Patients, Survivors and Caregivers

New studies released at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO) identify new strategies for easing the short- and long-term effects of cancer therapy and improving the quality of life of patients with cancer, as well as their caregivers.

We've made incredible strides in cancer treatment, and more cancer survivors are alive today than ever before. But oncology isn’t just about helping people live longer ...


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180 találat 9 oldalon - ebből zárolt tartalom 27642 db

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